April 4, 2020 – Trump pushes hydroxychloroquine to treat COVID-19; Fauci and media mock him; NIH published 2005 study extolling great results in treating SARS coronavirus with chloroquine

In Email/Dossier/Govt Corruption Investigations by Katie Weddington

Mainstream Media mocked Trump for months:

One of the most bizarre and disturbing aspects of President Trump’s nightly press briefings on the coronavirus pandemic is when he turns into a drug salesman. Like a cable TV pitchman hawking “male enhancement” pills, Trump regularly extols the virtues of taking hydroxychloroquine, a drug used to treat malaria and lupus, as a potential “game changer” that just might cure covid-19.

On Saturday, he even said: “I think people should — if it were me — in fact, I might do it anyway. I may take it. Okay? I may take it.” I’m not only the president of the Hair Club for Men, I’m also a client.

But the evidence that hydroxychloroquine could actually be an effective treatment is, at this point, extremely thin. Might it be some kind of aid in treating the disease, for some patients? Yes, it’s possible. But Trump’s enthusiasm for it is so out of proportion, and so relentless, that one has to ask: What the heck is going on here?

Some people are inclined to believe that Trump must have a financial motive, and the New York Times did report that he owns some stock in Sanofi, a company that makes the name-brand version of the drug. But I doubt that’s what’s at work. Instead, I think there are two reasons Trump is working so hard to convince everyone that hydroxychloroquine is a miracle cure, neither of which are about Trump’s own bank account.

The first is that Trump is listening to all the wrong people. We know that he finds those with advanced degrees extremely intimidating, activating his contempt and envy for experts. So when all the doctors and public health experts and epidemiologists tell him that while we can look into the potential of hydroxychloroquine, there’s no reason to think it’s going to be transformative, it makes him more, not less, convinced that it must be spectacular.

Trump compensates for his own insecurity by working to convince himself and everyone else that the experts don’t know what they’re talking about, and he knows more than them about everything. As he said in an appearance at the Centers for Disease Control and Prevention, “Every one of these doctors said, ‘How do you know so much about this?’ Maybe I have a natural ability.” The scientists standing with him neither burst out in laughter nor began weeping uncontrollably, a tribute to their self-control. (Read more: Washington Post, 4/07/2020)



Anthony Fauci also mocked Trump for months:



Interestingly, Fauci’s National Institute of Health published a study in August 2005 discussing the effectiveness of chloroquine against the SARS coronavirus:

Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

Results

We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.

Conclusion

Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds. (Read more: National Institute of Health, 8/22/2005)